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can be used in all areas where electrophysiological measurements are done today. In the area of ion channels and membrane transporters today this includes
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Target identification and validation Pharmacology Screening Drug safety / early ADME-Tox
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Furthermore the new possibilities offered with advanced bilayer techniques open new insights in novel areas of reseach. The combined observation of e.g. binding events and electrical currents provides the chance to elucidate
- the general influence of specific effectors binding to biomembranes (such as prions and synucleins).
- that certain biomolecules of not fully understood function alter membrane conductivity by binding to them.
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